RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
mir-30e
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
rattus norvegicus
Detection Methods
NA
Target
LOX1
Pathway
NF-KAPPA B SIGNALING PATHWAY
PubMed ID
Title
Exosomes released from mesenchymal stem cells overexpressing microRNA-30e ameliorate heart failure in rats with myocardial infarction
Year
2021
Function
"Exosomal miR-30e from rat bone marrow-derived mesenchymal stem cells (BMMSCs) markedly inhibited LOX1 expression, thereby downregulating the activity of the NF-KAPPA B p65/Caspase-9 signaling and ameliorating heart failure after myocardial infarction in rats."